BDBM221048 US9284322, varenicline::US9303017, Varenicline

SMILES C1[C@H]2CNC[C@@H]1c1cc3nccnc3cc21

InChI Key InChIKey=JQSHBVHOMNKWFT-DTORHVGOSA-N

Data  11 KI  2 IC50  2 EC50

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221048   

LigandPNGBDBM221048(US9284322, varenicline | US9303017, Varenicline)
Affinity DataKi:  0.120nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair